Yazarlar : Schütz N, Märker-Hermann E.
Yayın : Z Rheumatol.
Pubmed Linki : http://www.ncbi.nlm.nih.gov/pubmed/22286359
Konu : Myelom
Literatür İçeriği :
Abstract
Multiple myeloma (MM) is a disease of the elderly with an incidence of 4/100,000 per year and can occur as a comorbidity especially in elderly patients with rheumatoid arthritis (RA). For MM and also for RA interleukin-6 (IL-6) is a pathogenetically important cytokine in both disease events. This article presents the case of a female patient who achieved sustained remission of RA and stabilization of MM with quantitative reduction of paraprotein by treatment with tocilizumab. The question whether tocilizumab represents a meaningful treatment approach for treatment of RA when MM is also present will be discussed.
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